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Speculating on Health

Speculating on Health

Chapter:
(p.230) 9 Speculating on Health
Source:
Adverse Events
Author(s):
Jill A. Fisher
Publisher:
NYU Press
DOI:10.18574/nyu/9781479877997.003.0010

While healthy volunteers are concerned about the risks of studies, they are often much more vocal about the economic risk of not qualifying for studies. This chapter examines how being disqualified from studies through screen failures heightens their sense of risk as they attempt to earn income through clinical trials. It also considers how the screening process itself profoundly influences their health behaviors even outside of their study participation, including maintaining a healthy weight, eating nutritious food, consuming vitamins and supplements, and abstaining from deleterious substances, such as alcohol, tobacco, and illicit drugs. These actions on the part of healthy volunteers, which contribute to their model organism status, indicate that Phase I participation could counterintuitively improve their general health even as they expose themselves to the unknown risks of investigational drugs.

Keywords:   Phase I trials, healthy volunteers, model organism, economic risk, qualifying, screen failure, health-promoting behavior

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